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Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F08%3A00109193" target="_blank" >RIV/00216208:11160/08:00109193 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3

  • Original language description

    In the present study, we produced recombinant AKR1C3 and provided evidence that this AKR1C3 member catalyzes the inactivation of oracin and doxorubicin with high efficiency

  • Czech name

    Inaktivace protinádorových léčiv doxorubicinu a oracinu vlivem aldo-ketoreduktasy (AKR) 1C3

  • Czech description

    V předložené práci je popsána příprava rekombinantní formy AKR1C3 a poskytnut důkaz, že příslušný enzym velice účinně katalyzuje inaktivaci oracinu i doxorubicinu

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Toxicology Letters

  • ISSN

    0378-4274

  • e-ISSN

  • Volume of the periodical

    181

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

    000260145000001

  • EID of the result in the Scopus database