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Two-column Sequential Injection Chromatography - New approach for fast and effective analysis and its comparison with gradient elution chromatography

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F10%3A00300543" target="_blank" >RIV/00216208:11160/10:00300543 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Two-column Sequential Injection Chromatography - New approach for fast and effective analysis and its comparison with gradient elution chromatography

  • Original language description

    This work presents novel approach in low-pressure chromatography flow systems - two-column Sequential Injection Chromatography (2-C SIC) and its comparison with gradient elution chromatography on the same instrument. The system was equipped with two different chromatographic columns (connected to selection valve in parallel design) for isocratic separation and determination of all components in composed anti-inflammatory pharmaceutical preparation (tablets). The sample was first injected on the first column of length 30mm where less retained analytes were separated and then the sample was injected on the second column of length 10mmwhere more retained analytes were separated. The new two-column chromatographic set-up shows evident advantages as compared with single-column gradient method.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP203%2F08%2FP338" target="_blank" >GP203/08/P338: Using of monolithic column and LPME in sequential injection chromatography for drug analysis and biological samples pretreatment</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytica Chimica Acta

  • ISSN

    0003-2670

  • e-ISSN

  • Volume of the periodical

    668

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

    000278306800011

  • EID of the result in the Scopus database