A TLC Study of the Lipophilicity of New Antimycobacterial Active Benzoxazine Derivatives Containing a Thioxo Group

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F11%3A10099495" target="_blank" >RIV/00216208:11160/11:10099495 - isvavai.cz</a>
Result on the web
<a href="http://www.akademiai.com/content/r0623603161047h0/fulltext.pdf" target="_blank" >http://www.akademiai.com/content/r0623603161047h0/fulltext.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1556/JPC.24.2011.3.3" target="_blank" >10.1556/JPC.24.2011.3.3</a>

Result language
angličtina
Original language name
A TLC Study of the Lipophilicity of New Antimycobacterial Active Benzoxazine Derivatives Containing a Thioxo Group
Original language description
Experimental R(M) values of a series of 3-(4-alkylphenyl)-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 3-(4-alkylphenyl)-2H-1,3-benzoxazine-2,4(3H)-dithiones were obtained by a reversed-phase TLC system. The mobile phase was a phosphate buffer with volumefractions of acetone between 80 and 60%. The retention constants R(M)(0) were compared with the partition coefficients calculated using different software products. The lipophilicity contributions of the sub-stituents were compared with the pi constants.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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