Effect of Substitution on the Antimycobacterial Activity of 2-(Substituted benzyl)sulfanyl Benzimidazoles, Benzoxazoles, and Benzothiazoles - A Quantitative Structure-Activity Relationship Study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F11%3A10099573" target="_blank" >RIV/00216208:11160/11:10099573 - isvavai.cz</a>
Result on the web
<a href="http://www.jstage.jst.go.jp/article/cpb/59/2/179/_pdf" target="_blank" >http://www.jstage.jst.go.jp/article/cpb/59/2/179/_pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1248/cpb.59.179" target="_blank" >10.1248/cpb.59.179</a>

Result language
angličtina
Original language name
Effect of Substitution on the Antimycobacterial Activity of 2-(Substituted benzyl)sulfanyl Benzimidazoles, Benzoxazoles, and Benzothiazoles - A Quantitative Structure-Activity Relationship Study
Original language description
A set of the previously published 2-(substituted benzyl)sulfanyl benzimidazoles, benzoxazoles, and benzothiazoles has been analyzed by the methods of multidimensional analysis (exploratory analysis, 2D-nonlinear mapping - NLM, principal component analysis - PCA, factor analysis - FA, multiple linear regression - MLR). The effect of substitution on the antimycobacterial activity has been predicted.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
<a href="/en/project/NS10367" target="_blank" >NS10367: Evaluation and development of new perspective antimycobacterial drugs and prodrugs active against multidrug resistant strains</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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