Healthy adherer effect - the pitfall in the interpretation of the effect of medication adherence on health outcomes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F14%3A10145973" target="_blank" >RIV/00216208:11160/14:10145973 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/jep.12095/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/jep.12095/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jep.12095" target="_blank" >10.1111/jep.12095</a>

Result language
angličtina
Original language name
Healthy adherer effect - the pitfall in the interpretation of the effect of medication adherence on health outcomes
Original language description
Rationale, Aims and Objectives: Monitoring adherence to therapy is the subject of many studies. Different designs of research works may cause bias and subsequent unavailability to compare results. Healthy adherer effect (HAE) is a type of bias reflectingpatient behaviour. It cannot be easily monitored in study population and can favourably affect health outcomes that may be incorrectly attributed to drug therapy. The aim of this article was to draw attention to HAE and characterize studies concerning the impact of HAE in relation to medication adherence and health outcomes. Methods: Review of English literature from PubMed database identified all non-experimental studies dealing with HAE. Studies that met inclusion criteria were analysed in respect ofoccurrence and impact of HAE. Results: Six studies were identified - two randomized controlled and four cohort studies. Significant occurrence of HAE in relation to mortality was not observed while one study indicated the presence of HAE
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FQ - Public health system, social medicine
OECD FORD branch
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Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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