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Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312623" target="_blank" >RIV/00216208:11160/15:10312623 - isvavai.cz</a>

  • Result on the web

    <a href="http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201500620/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201500620/full</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/ejoc.201500620" target="_blank" >10.1002/ejoc.201500620</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones

  • Original language description

    A new synthetic route towards chiral 3,5-disubstituted pyrrol-2-ones by starting from amino acids has been developed. The sequence features the conversion of amino acids into their corresponding alkynoic acid derivative followed by a Pd-catalyzed hydrostannylation of the triple bond and Stille cross-coupling reaction. A series of lactam analogues of antifungal 3-(aryl)-5-hydroxymethyl-2,5-dihydrofuran-2-ones have thus been prepared.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Organic Chemistry

  • ISSN

    1434-193X

  • e-ISSN

  • Volume of the periodical

    2015

  • Issue of the periodical within the volume

    24

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    5414-5423

  • UT code for WoS article

    000359703900015

  • EID of the result in the Scopus database

    2-s2.0-84939126535