Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312623" target="_blank" >RIV/00216208:11160/15:10312623 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201500620/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201500620/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ejoc.201500620" target="_blank" >10.1002/ejoc.201500620</a>
Alternative languages
Result language
angličtina
Original language name
Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones
Original language description
A new synthetic route towards chiral 3,5-disubstituted pyrrol-2-ones by starting from amino acids has been developed. The sequence features the conversion of amino acids into their corresponding alkynoic acid derivative followed by a Pd-catalyzed hydrostannylation of the triple bond and Stille cross-coupling reaction. A series of lactam analogues of antifungal 3-(aryl)-5-hydroxymethyl-2,5-dihydrofuran-2-ones have thus been prepared.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Organic Chemistry
ISSN
1434-193X
e-ISSN
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Volume of the periodical
2015
Issue of the periodical within the volume
24
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
5414-5423
UT code for WoS article
000359703900015
EID of the result in the Scopus database
2-s2.0-84939126535