Synthesis of a molecularly imprinted sorbent for selective solid-phase extraction of beta-N-methylamino-L-alanine

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312832" target="_blank" >RIV/00216208:11160/15:10312832 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0039914015301806" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0039914015301806</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.talanta.2015.07.052" target="_blank" >10.1016/j.talanta.2015.07.052</a>

Result language

angličtina

Original language name

Synthesis of a molecularly imprinted sorbent for selective solid-phase extraction of beta-N-methylamino-L-alanine

Original language description

The aim of the work was to synthesize a molecularly imprinted material for the selective solid-phase extraction (SPE) of beta-N-methylamino-L-alanine (L-2-amino-3-methylpropionic acid; BMAA) from cyanobacterial extracts. BMAA and its structural analogs that can be used as template are small, polar and hydrophilic molecules. These molecules are poorly soluble in organic solvents that are commonly used for the synthesis of acrylic-based polymers. Therefore, a sol gel approach was chosen to carry out the synthesis and the resulting sorbents were evaluated with different extraction procedures in order to determine their ability to selectively retain BMAA. The presence of imprinted cavities in the sorbent was demonstrated by comparing elution profiles obtained by using molecularly imprinted silica (MIS) and non-imprinted silica (NIS) as a control. The molecularly imprinted solid-phase extraction (MISPE) procedure was first developed in a pure medium (acetonitrile) and further optimized for

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Talanta

ISSN

0039-9140

e-ISSN

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Volume of the periodical

144

Issue of the periodical within the volume

November

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

1021-1029

UT code for WoS article

000363346200139

EID of the result in the Scopus database

2-s2.0-84938630035