Indole-2-carboxamide derivatives: a patent evaluation of WO2015036412A1
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10317175" target="_blank" >RIV/00216208:11160/15:10317175 - isvavai.cz</a>
Result on the web
<a href="http://www.tandfonline.com/doi/full/10.1517/13543776.2015.1101066" target="_blank" >http://www.tandfonline.com/doi/full/10.1517/13543776.2015.1101066</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1517/13543776.2015.1101066" target="_blank" >10.1517/13543776.2015.1101066</a>
Alternative languages
Result language
angličtina
Original language name
Indole-2-carboxamide derivatives: a patent evaluation of WO2015036412A1
Original language description
Introduction: Hippocampal neurogenesis in adults is a new and attractive target for the treatment and prevention of neurodegenerative and neuro-psychiatric diseases. Recently, neurogenesis stimulating activity was observed in some of the commonly used small molecule drugs such as antidepressants and atypical antipsychotics. Stimulation of neurogenesis is attractive mainly due to its wide scope of application, ranging from depressions, schizophrenia, dementia, Parkinson's and Alzheimer's Disease to various brain injuries.Areas covered: New compounds based on 7-phenyl or 7-pyridinyl-1H-indole-2-carboxamide showed interesting neural stem cell proliferation inducing activity in vitro and were claimed as potential therapeutics for various neurodegenerativeand neuropsychiatric diseases as well as brain injuries. The potential of the presented compounds is evaluated with respect to other small molecule neurogenesis inducers in literature.Expert opinion: Nanomolar in vitro activities of prese
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Expert Opinion on Therapeutic Patents
ISSN
1354-3776
e-ISSN
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Volume of the periodical
25
Issue of the periodical within the volume
12
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
1487-1494
UT code for WoS article
000366528500003
EID of the result in the Scopus database
2-s2.0-84949764924