Copper(II) Sulfate Stimulates Scopoletin Production in Cell Suspension Cultures of Angelica archangelica

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F17%3A10365366" target="_blank" >RIV/00216208:11160/17:10365366 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Copper(II) Sulfate Stimulates Scopoletin Production in Cell Suspension Cultures of Angelica archangelica

Original language description

Plant tissue cultures represent an attractive alternative source of valuable natural substances. Many strategies have been proposed for improving production yields, among others, elicitation with heavy metals. In this work, the effect was investigated of copper(II) sulfate (at concentrations of 0, 0.1, 0.5, 1, 5, 10, 50, 100, and 200 mu M) on scopoletin production, as well as on cell growth in Angelica archangelica (angelica) suspension cultures with the cultures maintained in the dark and in the light. Copper(II) sulfate up to 100 mu M did not significantly affect either fresh or dry biomass in the cultures grown in either the dark or light, but at 200 mu M they were slightly reduced. Copper(II) sulfate stimulated accumulation of scopoletin in a dose-dependent manner both in the cells and in the culture medium. Moreover, concerning scopoletin production, the cultures showed different sensitivity to copper ions depending on light conditions. The highest yields of scopoletin were found at copper concentrations of 5-50 mu M and 50 mu M in the light- and dark-grown cultures, respectively. Copper(II) sulfate has proved to be a suitable elicitor for improvement of scopoletin accumulation in cell suspension cultures of A. archangelica.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Natural Product Communications

ISSN

1934-578X

e-ISSN

—

Volume of the periodical

12

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

2

Pages from-to

1779-1780

UT code for WoS article

000417552000032

EID of the result in the Scopus database

2-s2.0-85035243120