Ceramides in the skin barrier
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F17%3A10371812" target="_blank" >RIV/00216208:11160/17:10371812 - isvavai.cz</a>
Result on the web
<a href="http://www.degruyter.com/view/j/afpuc.2017.64.issue-2/afpuc-2017-0004/afpuc-2017-0004.xml" target="_blank" >http://www.degruyter.com/view/j/afpuc.2017.64.issue-2/afpuc-2017-0004/afpuc-2017-0004.xml</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/afpuc-2017-0004" target="_blank" >10.1515/afpuc-2017-0004</a>
Alternative languages
Result language
angličtina
Original language name
Ceramides in the skin barrier
Original language description
The skin barrier, which is essential for human survival on dry land, is located in the uppermost skin layer, the stratum corneum. The stratum corneum consists of corneocytes surrounded by multilamellar lipid membranes that prevent excessive water loss from the body and entrance of undesired substances from the environment. To ensure this protective function, the composition and organization of the lipid membranes is highly specialized. The major skin barrier lipids are ceramides, fatty acids and cholesterol in an approximately equimolar ratio. With hundreds of molecular species of ceramide, skin barrier lipids are a highly complex mixture that complicate the investigation of its behaviour. In this minireview, the structures of the major skin barrier lipids, formation of the stratum corneum lipid membranes and their molecular organization are described.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/GC16-25687J" target="_blank" >GC16-25687J: Interdependencies between Inflammatory Processes and Barrier Lipids in Diseased Skin</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Pharmaceutical Journal
ISSN
2453-6725
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
28-35
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85038365915