In vitro antimicrobial activity of natural substances convenient for use in animal breeding instead of antibiotics

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F20%3A10410638" target="_blank" >RIV/00216208:11160/20:10410638 - isvavai.cz</a>

Alternative codes found

RIV/60162694:G44__/20:00555992 RIV/00216208:11150/20:10410638 RIV/00179906:_____/20:10410638

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=loTBbz0FJW" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=loTBbz0FJW</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.31482/mmsl.2019.018" target="_blank" >10.31482/mmsl.2019.018</a>

Result language

angličtina

Original language name

In vitro antimicrobial activity of natural substances convenient for use in animal breeding instead of antibiotics

Original language description

The increasing antibiotic resistance of microbial pathogens isolated from farm animals tissues and the environment has been the one of the most important challenges associated with the use of antibiotics. In order to achieve better production on a farm, animal feed is enriched with antibiotics often originally intended for therapeutic purposes, which may lead to notable increases in microbial resistance. One possible approach to decreasing the excessive use of antibiotics in livestock as well as antimicrobial resistance is utilizing the antimicrobial properties of natural substances. The aim of this study was to evaluate the antimicrobial activity of natural substances including carvacrol, thymol, eugenol, gallic acid, octyl gallate, cnicin and usnic acid against a wide spectrum of microorganisms. Cnicin was the only compound which was isolated from the plant with use of column chromatography. The antimicrobial activities of these natural substances were determined on the basis of their minimum inhibitory, minimum bactericidal and minimum fungicidal concentrations using the microdilution method. This determination of antimicrobial activity revealed thymol and cnicin to be effective natural substances against all tested microorganisms. Octyl gallate had a strong inhibitory and bactericidal effect against grampositive bacteria and was the most effective against Candida strains. Usnic acid was shown to have the lowest minimum inhibitory concentrations for gram-positive bacteria. These results suggest the possible incorporation of natural substances in animal rearing in order to reduce the high amount of antibiotics which are not used directly to treat animal diseases.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

10606 - Microbiology

Project

<a href="/en/project/QI111A166" target="_blank" >QI111A166: Biotechnological processes in reproduction and pig breeding as a tool of the economic growth and competitive advantage.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Military Medical Science Letters - Vojenské zdravotnické listy

ISSN

0372-7025

e-ISSN

—

Volume of the periodical

89

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

12

Pages from-to

2-13

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85081567224