The interaction between the anticancer drug ellipticine and cytochromes P450 dictates its pharmacological efficiencies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F03%3A00000571" target="_blank" >RIV/00216208:11310/03:00000571 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
The interaction between the anticancer drug ellipticine and cytochromes P450 dictates its pharmacological efficiencies
Original language description
Five metabolites containining an oxygene atom in their molecules are generated from ellipticine by CYPs. Ellipticine inhibits microsomal CYP-dependent activities and interacts with CYPs exhibiting a reverse type binding spectrum.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GA203%2F01%2F0996" target="_blank" >GA203/01/0996: Study of molecular mechanism of anticancer effect of a chemotherapeutic, ellipticine</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemické listy
ISSN
0009-2770
e-ISSN
—
Volume of the periodical
97
Issue of the periodical within the volume
S
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
1
Pages from-to
117-117
UT code for WoS article
—
EID of the result in the Scopus database
—