Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F04%3A00006389" target="_blank" >RIV/00216208:11310/04:00006389 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor
Original language description
Regioisomer of chitobiose 13 with beta(1-->3) glycosidic bond and branched analog of chitotriose 25 having beta(1-->4) and beta(1-->3) glycosidic bonds, were prepared and tested as potential mimetics of natural oligosaccharide ligands for activating lectin receptors NKR-P1A and CD69 of natural killer (NK) cells. The structural requirements of NKR-P1 lectin receptor on effective mimetics of its natural ligands has been discussed. A significant binding activity of the branched trisaccharide 25 to the receptor CD69 was observed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F00%2F0071" target="_blank" >GA203/00/0071: Synthesis of cyclic oligosaccharides containing 2-amino-2-deoxy-hexopyranoses and study of their complexation activity</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Collection of Czechoslovak Chemical Communications
ISSN
0010-0765
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
9
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
24
Pages from-to
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UT code for WoS article
000224406800003
EID of the result in the Scopus database
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