Multicompartment Nanoparticles Formed by a Heparin-Mimicking Block Terpolymer in Aqueous Solutions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10000214" target="_blank" >RIV/00216208:11310/09:10000214 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Multicompartment Nanoparticles Formed by a Heparin-Mimicking Block Terpolymer in Aqueous Solutions

Original language description

A new amphiphilic block terpolymer poly((sulfamate-carboxylate)isoprene)-block-polystyrene-block-poly(ethylene oxide) was synthesized via the post polymerization reaction of the anionically prepared precursor block terpolymer polyisoprene-block-polystyrene-block-poly(ethylene oxide) with chlorosulfonyl isocyanate. The formation and structure of self-assemblies of the polyelectrolyte block terpolymer in dilute aqueous solutions were studied by light scattering, AFM, cryo-TEM, fluorometry, and H-1 NMR spectroscopy. In acidic solutions, the terpolymers self-assemble into kinetically trapped multicompartment micelles, with the core consisting of discrete PS and PISC domains and PEO in the shell. If the solution pH is adjusted to the alkaline region, the multicompartment micelles undergo an irreversible transition to regular micelles, with a PS core and a mixed shell formed by PEO and PISC blocks.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecules

ISSN

0024-9297

e-ISSN

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Volume of the periodical

42

Issue of the periodical within the volume

15

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

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UT code for WoS article

000268523400032

EID of the result in the Scopus database

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