Effect of Surfactants and Ionic Strength on Dissociation of Hydrochlorides of Phenothiazine Derivatives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10001235" target="_blank" >RIV/00216208:11310/09:10001235 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effect of Surfactants and Ionic Strength on Dissociation of Hydrochlorides of Phenothiazine Derivatives

Original language description

A study of the effect of the anionic surfactant dodecyl sulfate, the cationic surfactant carbethoxypentadecyl trimethyl ammonium bromide (Septonex), nonionic surfactant p-octyl phenyl polyoxyethylene (Triton X-100), and a strong electrolyte (KBr) on thedissociation of the hydrochlorides of two derivatives of phenothiazine (diethazine and fluphenazine) was made. It was found that sodium dodecyl sulfate increases the pKa value, whereas Septonex and Triton X-100 decrease this value. The presence of KBr suppresses the effect of the surfactants. A new method for the potentiometric determination of fluphenazine in an aqueous medium was proposed.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Analytical Letters

ISSN

0003-2719

e-ISSN

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Volume of the periodical

42

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

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UT code for WoS article

000264346800002

EID of the result in the Scopus database

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