On the Selective N-Methylation of BOC-Protected Amino Acids
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10112647" target="_blank" >RIV/00216208:11310/09:10112647 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/jo9016293" target="_blank" >http://dx.doi.org/10.1021/jo9016293</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jo9016293" target="_blank" >10.1021/jo9016293</a>
Alternative languages
Result language
angličtina
Original language name
On the Selective N-Methylation of BOC-Protected Amino Acids
Original language description
The selective N-methylation of BOC-protected valine with MeI and NaH in THF (i.e., in the presence of a free carboxyl group) has been attributed to the protection of the carboxylate by chelation to Na+. An alternative mechanism, involving the formation of the carbene intermediate generated from MeI and its insertion into the NMINUS SIGN H bond, has been ruled out by isotopic labeling.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Organic Chemistry
ISSN
0022-3263
e-ISSN
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Volume of the periodical
74
Issue of the periodical within the volume
21
Country of publishing house
US - UNITED STATES
Number of pages
3
Pages from-to
8425-8427
UT code for WoS article
000271113400056
EID of the result in the Scopus database
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