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X-ray structure, NMR and stability-in-solution study of 6-(furfurylamino)-9-(tetrahydropyran-2-yl)purine - A new active compound for cosmetology

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10057091" target="_blank" >RIV/00216208:11310/10:10057091 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389030:_____/10:00349821 RIV/61989592:15310/10:10217261

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    X-ray structure, NMR and stability-in-solution study of 6-(furfurylamino)-9-(tetrahydropyran-2-yl)purine - A new active compound for cosmetology

  • Original language description

    The crystal and molecular structure of 6-(furfurylamino)-9-(tetrahydropyran-2-yl)purine (1) was determined at 150(2) K. The compound crystallizes in monoclinic P2(1)/c space group with a = 10.5642(2), = 13.6174(3), c = 10.3742(2) angstrom, V = 1460.78(5)angstrom(3), Z = 4, R(F) = for 3344 unique reflections. The purine moiety and furfuryl ring are planar and the tetrahydropyran-2-yl is disordered in the ratio 1:3, probably due to the chiral carbon atom C(17). The individual H-1 and C-13 NMR signals were assigned by 20 correlation experiments such as H-1-H-1 COSY and ge-2D HSQC. Stability-in-solution was determined in methanol/water in acidic pH (3-7).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of molecular structure

  • ISSN

    0022-2860

  • e-ISSN

  • Volume of the periodical

    975

  • Issue of the periodical within the volume

    1-3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

    000280028600057

  • EID of the result in the Scopus database