Guanidinium Cations Pair with Positively Charged Arginine Side Chains in Water

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10103724" target="_blank" >RIV/00216208:11310/11:10103724 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/11:00360095
Result on the web
<a href="http://dx.doi.org/10.1021/jz2005495" target="_blank" >http://dx.doi.org/10.1021/jz2005495</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jz2005495" target="_blank" >10.1021/jz2005495</a>

Result language
angličtina
Original language name
Guanidinium Cations Pair with Positively Charged Arginine Side Chains in Water
Original language description
Using capillary electrophoresis and molecular dynamics simulations, we directly demonstrate that guanidinium cations exhibit an affinity for the positively charged side chains of arginine-containing peptides in aqueous solutions, while no such effect isobserved for sodium cations and/or lysine. Such a counterintuitive pairing between these two positively charged moieties has implications for destabilization and aggregation of arginine-rich proteins in guanidinium salt solutions.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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