Changes of Plasma Obestatin, Ghrelin and NPY in Anorexia and Bulimia Nervosa Patients Before and After a High-Carbohydrate Breakfast

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10105966" target="_blank" >RIV/00216208:11310/11:10105966 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/11:10614 RIV/00023761:_____/11:#0000169 RIV/00064165:_____/11:10614

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Changes of Plasma Obestatin, Ghrelin and NPY in Anorexia and Bulimia Nervosa Patients Before and After a High-Carbohydrate Breakfast

Original language description

Peptides ghrelin, obestatin and neuropeptide Y (NPY) play an important role in regulation of energy homeostasis, the imbalance of which is associated with eating disorders anorexia (AN) and bulimia nervosa (BN). The changes in ghrelin, obestatin and NPYplasma levels were investigated in AN and BN patients after administration of a high-carbohydrate breakfast (1604 kJ). Eight AN women (aged 25.4+-1.9; BMI: 15.8+-0.5), thirteen BN women (aged 22.0+-1.05; BMI: 20.1+-0.41) and eleven healthy women (aged 25.1+-1.16; BMI: 20.9+-0.40) were recruited for the study. We demonstrated increased fasting ghrelin in AN, but not in BN patients, while fasting obestatin and NPY were increased in both AN and BN patients compared to the controls. Administration of high-carbohydrate breakfast induced a similar relative decrease in ghrelin and obestatin plasma levels in all groups, while NPY remained increased in postprandial period in both patient groups. Ghrelin/obestatin ratio was lower in AN and BN com

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

—

Project

<a href="/en/project/NR9158" target="_blank" >NR9158: Postprandial response of ghrelin and other appetite-modulating hormones in patients with anorexia nervosa and bulimia nervosa</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

—

Volume of the periodical

60

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

9

Pages from-to

165-173

UT code for WoS article

000288563800016

EID of the result in the Scopus database

—