Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10107601" target="_blank" >RIV/00216208:11310/11:10107601 - isvavai.cz</a>

Result on the web

<a href="http://genomebiology.com/content/12/2/R20" target="_blank" >http://genomebiology.com/content/12/2/R20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/gb-2011-12-2-r20" target="_blank" >10.1186/gb-2011-12-2-r20</a>

Result language

angličtina

Original language name

Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

Original language description

We have produced a draft genome sequence of another group dictyostelid, Dictyostelium purpureum, and compare it to the D. discoideum genome. The assembly (8.41 x coverage) comprises 799 scaffolds totaling 33.0 Mb, comparable to the D. discoideum genome size. Sequence comparisons suggest that these two dictyostelids shared a common ancestor approximately 400 million years ago. In spite of this divergence, most orthologs reside in small clusters of conserved synteny. Comparative analyses revealed a core set of orthologous genes that illuminate dictyostelid physiology, as well as differences in gene family content. Interesting patterns of gene conservation and divergence are also evident, suggesting function differences; some protein families, such as thehistidine kinases, have undergone little functional change, whereas others, such as the polyketide synthases, have undergone extensive diversification. The abundant amino acid homopolymers encoded in both genomes are generally not found

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Genome Biology

ISSN

1474-760X

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

23

Pages from-to

1-23

UT code for WoS article

000289365600016

EID of the result in the Scopus database

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