Direct evidence of Toxoplasma-induced changes in serum testosterone in mice
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10108375" target="_blank" >RIV/00216208:11310/11:10108375 - isvavai.cz</a>
Result on the web
<a href="http://web.natur.cuni.cz/flegr/pdf/testomice.pdf" target="_blank" >http://web.natur.cuni.cz/flegr/pdf/testomice.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.exppara.2011.03.014" target="_blank" >10.1016/j.exppara.2011.03.014</a>
Alternative languages
Result language
angličtina
Original language name
Direct evidence of Toxoplasma-induced changes in serum testosterone in mice
Original language description
Latent toxoplasmosis is known to influence the morphology of infected persons and also increases the probability of the birth of male offspring in both humans and mice. All these traits can be related to the observed differences in the concentration of testosterone between Toxoplasma-infected and Toxoplasma-free subjects. However, it is not possible to decide, using the Toxoplasma-human model, whether toxoplasmosis influences the level of testosterone in the infected host or whether individuals with different levels of testosterone vary in the probability of toxoplasma infection. Here we studied changes in the testosterone levels in the latent phase of toxoplasmosis in laboratory mice artificially infected with cystogenic but relatively virulent strainT38 of T. gondii. We observed decreased testosterone levels in both female and male mice with latent toxoplasmosis in comparison to uninfected controls (P = 0.001). The present results indicate that Toxoplasma infection changes the conce
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Experimental Parasitology
ISSN
0014-4894
e-ISSN
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Volume of the periodical
128
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
3
Pages from-to
181-183
UT code for WoS article
000291497700001
EID of the result in the Scopus database
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