Light-activated nanofibre textiles exert antibacterial effects in the setting of chronic wound healing

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10127500" target="_blank" >RIV/00216208:11310/12:10127500 - isvavai.cz</a>
Alternative codes found
RIV/61388980:_____/12:00378022 RIV/61388955:_____/12:00378022 RIV/00064173:_____/12:43906388 RIV/00216208:11120/12:43906388
Result on the web
<a href="http://dx.doi.org/10.1111/j.1600-0625.2012.01536.x" target="_blank" >http://dx.doi.org/10.1111/j.1600-0625.2012.01536.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1600-0625.2012.01536.x" target="_blank" >10.1111/j.1600-0625.2012.01536.x</a>

Result language
angličtina
Original language name
Light-activated nanofibre textiles exert antibacterial effects in the setting of chronic wound healing
Original language description
he maintenance of an aseptic environment for chronic wounds is one of the most challenging tasks in the wound-healing process. Furthermore, the emergence of antibiotic-resistant bacterial strains is on the rise, rendering conventional treatments less effective. A new antibacterial material consisting of a polyurethane Tecophilic(TM) nanofibre textile (NT) that was prepared by electrospinning and doped by a tetraphenylporphyrin (TPP) photosensitizer activated by visible light was tested for use in woundbeds and bandages. In vitro experiments were performed to assess the antibacterial activity of the textile against three bacterial strains. Furthermore, the new textile was tested in 162 patients with chronic leg ulcers. A complete inhibition of in vitrogrowth of the three tested bacterial strains was observed on the surface of NTs that had been illuminated with visible light and was clinically demonstrated in 89 patients with leg ulcers. The application of the textiles resulted in a 35
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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