Synthesis of Ferrocenestrone: the First Metallocene Based Steroid Analogue

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10127556" target="_blank" >RIV/00216208:11310/12:10127556 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/12:00387886 RIV/61388963:_____/12:00387886
Result on the web
<a href="http://dx.doi.org/10.1002/chem.201200687" target="_blank" >http://dx.doi.org/10.1002/chem.201200687</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chem.201200687" target="_blank" >10.1002/chem.201200687</a>

Result language
angličtina
Original language name
Synthesis of Ferrocenestrone: the First Metallocene Based Steroid Analogue
Original language description
Ferrocenestrone, the first steroid derivative containing a metallocene moiety, was stereoselectively prepared (see scheme). The key steps included the enantioselective functionalization of ferrocene, elongation of the side chain, intramolecular enyne metathesis, Diels-Alder reaction, heterogeneous hydrogenation of the sterically hindered double bond, and finally inversion of the configuration at C13.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Result description