Derivatization chemistry of the double-decker dicobalt sandwich ion targeted to design biologically active substances

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10127593" target="_blank" >RIV/00216208:11310/12:10127593 - isvavai.cz</a>
Alternative codes found
RIV/61388980:_____/12:00383643 RIV/61388963:_____/12:00383643
Result on the web
<a href="http://dx.doi.org/10.1351/PAC-CON-12-04-03" target="_blank" >http://dx.doi.org/10.1351/PAC-CON-12-04-03</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1351/PAC-CON-12-04-03" target="_blank" >10.1351/PAC-CON-12-04-03</a>

Result language
angličtina
Original language name
Derivatization chemistry of the double-decker dicobalt sandwich ion targeted to design biologically active substances
Original language description
A synthesis of the first double-decker sandwich ion [(1',2'-C 2B 9H 11)-3,3'-Co-(1,2-C 2B 8H 10)-6,3"-Co-(1",2"-C 2B 9H 11)] 2- (DD 2-) derivatives is described, having been developed in connection with our search for biologically active substances. A series of B-substituted hydroxyl derivatives was prepared by direct hydroxylation of the ion using aqueous sulfuric acid. Two isomers of monohydroxy derivatives were isolated. The main product was substituted at the central "canastide" ion fragment, whereas the substitution site for the minor isomer corresponded to a B(8) atom of one of the terminal 11-vertex dicarbollide parts. Similarly, the disubstitution occurred slightly more preferentially on the "canastide" fragment providing the main isomeric derivative with a symmetric structure. The cesium salt of this ion was characterized by X-ray diffraction. Two other isomeric species have one substituent sitting on the "canastide" ion and the second present on the dicarbollide ligand in apa
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CA - Inorganic chemistry
OECD FORD branch
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Project
<a href="/en/project/IAAX00320901" target="_blank" >IAAX00320901: Functionalized boron clusters as viral enzyme inhihitors</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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