On the stability of the bioactive flavonoids quercetin and luteolin under oxygen-free conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10127724" target="_blank" >RIV/00216208:11310/12:10127724 - isvavai.cz</a>
Alternative codes found
RIV/61388955:_____/12:00375920
Result on the web
<a href="http://dx.doi.org/10.1007/s00216-011-5504-3" target="_blank" >http://dx.doi.org/10.1007/s00216-011-5504-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00216-011-5504-3" target="_blank" >10.1007/s00216-011-5504-3</a>
Alternative languages
Result language
angličtina
Original language name
On the stability of the bioactive flavonoids quercetin and luteolin under oxygen-free conditions
Original language description
The natural flavonoid compounds quercetin (3,3',4',5,7-pentahydroxyflavone) and luteolin (3',4',5,7-tetrahydroxyflavone) are important bioactive compounds with antioxidative, anti-allergic, and anti-inflammatory properties. However, both are unstable when exposed to atmospheric oxygen, which causes degradation and complicates their analytical determinations. The oxidative change of these flavonoids was observed and followed by UV-visible spectrophotometry, both in aqueous and ethanolic solutions. The distribution of the degradation products in aqueous media was monitored by LC-MS and LC-DAD analysis. The amounts of oxidative reaction products increase with the exposure time. The oxidative degradation reduces the pharmacological efficiency of these antioxidants and renders analytical determination inaccurate. The oxidative changes in flavonoid test solutions can explain the inconsistent dissociation constants reported in the literature. Dissociation constants of quercetin and luteolin w
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F09%2F1607" target="_blank" >GA203/09/1607: Electrochemistry of natural pigments and their host-guest complexes.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical and Bioanalytical Chemistry
ISSN
1618-2642
e-ISSN
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Volume of the periodical
402
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
975-982
UT code for WoS article
000298645300039
EID of the result in the Scopus database
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