Sphingosine and clavaminol H derivatives bearing fluorinated chains and their cytotoxic activity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10132861" target="_blank" >RIV/00216208:11310/12:10132861 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/12:00380635
Result on the web
<a href="http://dx.doi.org/10.1016/j.jfluchem.2012.06.005" target="_blank" >http://dx.doi.org/10.1016/j.jfluchem.2012.06.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jfluchem.2012.06.005" target="_blank" >10.1016/j.jfluchem.2012.06.005</a>

Result language
angličtina
Original language name
Sphingosine and clavaminol H derivatives bearing fluorinated chains and their cytotoxic activity
Original language description
Microwave induced cross-metathesis of perfluoroalkylated propenes with a substituted allyl alcohol is a simple and straightforward method for the synthesis of sphingosine derivatives possessing perfluoroalkyl chains. One of the prepared compounds was converted into the fluorinated clavaminol H derivative and its deacetylated congener. Selected compounds were subjected to preliminary testing for cytotoxic activity on several cancer cell lines.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
<a href="/en/project/LC06077" target="_blank" >LC06077: Center of Chemical Genetics</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)