Flavin-cyclodextrin conjugates: effect of the structure on the catalytic activity in enantioselective sulfoxidations

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10132880" target="_blank" >RIV/00216208:11310/12:10132880 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/12:00388435 RIV/60461373:22310/12:43894881
Result on the web
<a href="http://dx.doi.org/10.1016/j.tetasy.2012.10.017" target="_blank" >http://dx.doi.org/10.1016/j.tetasy.2012.10.017</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tetasy.2012.10.017" target="_blank" >10.1016/j.tetasy.2012.10.017</a>

Result language
angličtina
Original language name
Flavin-cyclodextrin conjugates: effect of the structure on the catalytic activity in enantioselective sulfoxidations
Original language description
A series of flavin cyclodextrin conjugates has been prepared and tested in the enantioselective oxidations of prochiral aromatic and aliphatic sulfides with hydrogen peroxide. The newly prepared conjugates contain isoalloxazinium or alloxazinium moietiesattached to the primary rim of alpha- and beta-cyclodextrins at the C-6 positions. In addition, flavinium units were attached to the secondary rim of the beta-cyclodextrin macrocycle. The relationship between the structural features and the catalytic performance of the conjugates, including those recently reported by us, was analyzed. The rate and enantioselectivity of the sulfoxidations catalyzed by flavin cyclodextrin conjugates are influenced mainly by the size of the cyclodextrin cavity, the type of flavin unit (alloxazine or isoalloxazine), and by the relative orientation of the flavin and cyclodextrin moieties.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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