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Methylene-bis[(aminomethyl)phosphinic acids]: synthesis, acid-base and coordination properties

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10139594" target="_blank" >RIV/00216208:11310/13:10139594 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1039/c2dt32045b" target="_blank" >http://dx.doi.org/10.1039/c2dt32045b</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/c2dt32045b" target="_blank" >10.1039/c2dt32045b</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Methylene-bis[(aminomethyl)phosphinic acids]: synthesis, acid-base and coordination properties

  • Original language description

    Three symmetrical methylene-bis[(aminomethyl)phosphinic acids] bearing different substituents on the central carbon atom, (NH2CH2) PO2H-C(R-1)(R-2)-PO2H(CH2NH2) where R-1 = OH, R-2 = Me (H2L1), R-1 = OH, R-2 = Ph (H2L2) and R-1, R-2 = H (H2L3), were synthesized. Acid-base and complexing properties of the ligands were studied in solution as well as in the solid state. The ligands show unusually high basicity of the nitrogen atoms (log K-1 = 9.5-10, log K-2 = 8.5-9) if compared with simple (aminomethyl) phosphinic acids and, consequently, high stability constants of the complexes with studied divalent metal ions. The study showed the important role of the hydroxo group attached to the central carbon atom of the geminal bis(phosphinate) moiety. Deprotonation of the hydroxo group yields the alcoholate anion which tends to play the role of a bridging ligand and induces formation of polynuclear complexes. Solid-state structures of complexes [H2N=C(NH2)(2)][Cu-2(H-1L2)(2)]CO3 center dot 10H(2

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CA - Inorganic chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GPP207%2F10%2FP153" target="_blank" >GPP207/10/P153: Geminal diphosphinates ? a route to improved complexation rates of macrocyclic ligands for biomedical applications</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Dalton Transactions

  • ISSN

    1477-9226

  • e-ISSN

  • Volume of the periodical

    42

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    2414-2422

  • UT code for WoS article

    000313804200013

  • EID of the result in the Scopus database