A simplified technique for evaluating human CCR5 genetic polymorphism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10173228" target="_blank" >RIV/00216208:11310/13:10173228 - isvavai.cz</a>
Result on the web
<a href="http://www.bioone.org/doi/full/10.1525/abt.2013.75.9.13" target="_blank" >http://www.bioone.org/doi/full/10.1525/abt.2013.75.9.13</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1525/abt.2013.75.9.13" target="_blank" >10.1525/abt.2013.75.9.13</a>
Alternative languages
Result language
angličtina
Original language name
A simplified technique for evaluating human CCR5 genetic polymorphism
Original language description
To involve students in thinking about the problem of AIDS (which is important in the view of non-decreasing infection rates) we established a practical lab using a simplified method of Thomas (2004) to determine the polymorphism of HIV co-receptor CCR5 from students' own epithelial cells. CCR5 is a receptor involved in inflammatory processes, which has been misused by some pathogens, including HIV, to enter host cells. As a result, a defective allele CCR5-?32 has been enriched in some populations. Due to the interesting story and hands-on work with their own tissue students were absorbed by this 2 hour practical.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
AM - Pedagogy and education
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0506" target="_blank" >1M0506: Center of Molecular and Cellular Immunology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů