Effect of posttranslational modifications on enzyme function and assembly

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10190110" target="_blank" >RIV/00216208:11310/13:10190110 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/13:00422889

Result on the web

<a href="http://dx.doi.org/10.1016/j.jprot.2013.03.025" target="_blank" >http://dx.doi.org/10.1016/j.jprot.2013.03.025</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jprot.2013.03.025" target="_blank" >10.1016/j.jprot.2013.03.025</a>

Result language

angličtina

Original language name

Effect of posttranslational modifications on enzyme function and assembly

Original language description

The detailed examination of enzyme molecules by mass spectrometry and other techniques continues to identify hundreds of distinct PTMs. Recently, global analyses of enzymes using methods of contemporary proteomics revealed widespread distribution of PTMson many key enzymes distributed in all cellular compartments. Critically, patterns of multiple enzymatic and nonenzymatic PTMs within a single enzyme are now functionally evaluated providing a holistic picture of a macromolecule interacting with low molecular mass compounds, some of them being substrates, enzyme regulators, or activated precursors for enzymatic and nonenzymatic PTMs. Multiple PTMs within a single enzyme molecule and their mutual interplays are critical for the regulation of catalytic activity. Full understanding of this regulation will require detailed structural investigation of enzymes, their structural analogs, and their complexes. Further, proteomics is now integrated with molecular genetics, transcriptomics, and o

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Proteomics

ISSN

1874-3919

e-ISSN

—

Volume of the periodical

92

Issue of the periodical within the volume

Special issue SI

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

30

Pages from-to

80-109

UT code for WoS article

000328518000007

EID of the result in the Scopus database

—