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Sarcosine as a Potential Prostate Cancer Biomarker-A Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10190913" target="_blank" >RIV/00216208:11310/13:10190913 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/13:00070630 RIV/00216208:11130/13:10190913 RIV/00216305:26620/13:PU104580 RIV/00064203:_____/13:10190913

  • Result on the web

    <a href="http://dx.doi.org/10.3390/ijms140713893" target="_blank" >http://dx.doi.org/10.3390/ijms140713893</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/ijms140713893" target="_blank" >10.3390/ijms140713893</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sarcosine as a Potential Prostate Cancer Biomarker-A Review

  • Original language description

    Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that fact, there is great interest in the finding of new markers including amino acids, proteins or nucleic acids. Prostate specific antigen (PSA) is commonly used and is the most important biomarker of CaP. This marker can only be detected in blood and its sensitivity is approximately 80%. Moreover, early stages cannot be diagnosed using this protein. Currently, there does not exist a test for diagnosis of early stages of prostate cancer. This fact motivates us to find markers sensitive to the early stages of CaP, which are easily detectedin body fluids including urine. A potential is therefore attributed to the non-protein amino acid sarcosine, which is generated by glycine-N-methyltransferase in its biochemical cycle. In this review, we summarize analytical methods for q

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Molecular Sciences

  • ISSN

    1422-0067

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    16

  • Pages from-to

    13893-13908

  • UT code for WoS article

    000322171700060

  • EID of the result in the Scopus database