Identification of Rice Proteins Recognized by the IgE Antibodies of Patients with Food Allergies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10193098" target="_blank" >RIV/00216208:11310/13:10193098 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/13:00425462 RIV/00064165:_____/13:10193098 RIV/00216208:11110/13:10193098

Result on the web

<a href="http://dx.doi.org/10.1021/jf402759f" target="_blank" >http://dx.doi.org/10.1021/jf402759f</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/jf402759f" target="_blank" >10.1021/jf402759f</a>

Result language

angličtina

Original language name

Identification of Rice Proteins Recognized by the IgE Antibodies of Patients with Food Allergies

Original language description

Similarity among food allergens is a great problem affecting the specificity of diagnosis and treatment of allergic patients. We have observed that 80% of patients with food (including wheat) and pollen allergies have increased IgE antibodies against rice proteins. By immunoblotting, we documented that boiling decreased solubility and IgE reactivity of PBS-extracted rice and wheat proteins, yet in SDS extracts this reactivity was only slightly changed. The sera of patients highly positive on the IgE immunoblot and positive in basophil activation and skin prick test with boiled rice components were used for characterizing the IgE-binding proteins separated by 1D or 2D electrophoresis. Using mass spectrometry, we identified 22 rice SDS soluble proteins.Six of them were new thermostable potential rice allergens: glutelin C precursor, granule-bound starch synthase 1 protein, disulfide isomerase-like 1-1 protein, hypothetical protein OsI_13867, putative acid phosphatase precursor 1, and a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Agricultural and Food Chemistry

ISSN

0021-8561

e-ISSN

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Volume of the periodical

61

Issue of the periodical within the volume

37

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

8851-8860

UT code for WoS article

000330096300018

EID of the result in the Scopus database

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