Modules in the metabolic network of E.coli with regulatory interactions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10209674" target="_blank" >RIV/00216208:11310/13:10209674 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/13:00423768
Result on the web
<a href="http://dx.doi.org/10.1504/IJDMB.2013.055500" target="_blank" >http://dx.doi.org/10.1504/IJDMB.2013.055500</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1504/IJDMB.2013.055500" target="_blank" >10.1504/IJDMB.2013.055500</a>
Alternative languages
Result language
angličtina
Original language name
Modules in the metabolic network of E.coli with regulatory interactions
Original language description
We examine the modular structure of the metabolic network when combined with the regulatory network representing direct regulation of enzymes by small metabolites in E. coli. We introduce novel clustering algorithm and compare it with mainstream module detection method based on simulated annealing. Both methods identify the similar modular core. Slight but significant increase in modularity is observed after regulatory interactions addition. We also identify new functional modules in the combined network, which cannot be detected in the metabolic network only. Regulatory loops in the modules are the source of their autonomy, and allow us to hypothesise about module function.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JD - Use of computers, robotics and its application
OECD FORD branch
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Result continuities
Project
<a href="/en/project/OC09078" target="_blank" >OC09078: Analysis and modelling of complex network using the methods of statistical physics</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Data Mining and Bioinformatics
ISSN
1748-5673
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
2
Country of publishing house
ES - SPAIN
Number of pages
15
Pages from-to
188-202
UT code for WoS article
000324166200004
EID of the result in the Scopus database
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