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Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10191360" target="_blank" >RIV/00216208:11310/14:10191360 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023736:_____/14:00010768

  • Result on the web

    <a href="http://onlinelibrary.wiley.com/doi/10.1002/jmv.23841/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/jmv.23841/full</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/jmv.23841" target="_blank" >10.1002/jmv.23841</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population

  • Original language description

    JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Czech Republic. Serum samples from 991 healthy individuals (age range: 6-64 years) were examined by enzyme-linked immunoassay (ELISA) using virus-like particles (VLPs) based on the major VP1capsid proteins of these viruses. Overall, serum antibodies against MCPyV, JCV, and BKV were found in 63%, 57%, and 69%, respectively, of this population. For all three viruses, these rates were associated with age; the occurrence of antibodies against MCPyV and JCV was highest for those older than 59 years, while the occurrence of antibodies against BKV was highest in those aged 10-19 years and 20-29 years. This is the first large study to determine the seroprevalence rates for BKV, JCV

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP304%2F10%2F1511" target="_blank" >GAP304/10/1511: Study of the novel human polyomavirus (MCPyV) discovered in Merkel cell carcinomas.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Medical Virology

  • ISSN

    0146-6615

  • e-ISSN

  • Volume of the periodical

    86

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    1560-1568

  • UT code for WoS article

    000339486600014

  • EID of the result in the Scopus database