The application of antimicrobial photodynamic therapy on S. aureus and E. coli using porphyrin photosensitizers bound to cyclodextrin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10209524" target="_blank" >RIV/00216208:11310/14:10209524 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/14:33149452

Result on the web

<a href="http://dx.doi.org/10.1016/j.micres.2013.07.005" target="_blank" >http://dx.doi.org/10.1016/j.micres.2013.07.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.micres.2013.07.005" target="_blank" >10.1016/j.micres.2013.07.005</a>

Result language

angličtina

Original language name

The application of antimicrobial photodynamic therapy on S. aureus and E. coli using porphyrin photosensitizers bound to cyclodextrin

Original language description

Photodynamic therapy is usually used against malignant and non-malignant tumors. Nowadays, due to resistance of bacterial strains, we are looking for a new antimicrobial strategy to destroy bacteria with minimal invasive consequences. The worldwide increase in antibiotic resistance among different classes of gram-positive and gram-negative bacteria has led to the search for alternative anti-microbial therapies such as antimicrobial PDT (aPDT). Development antimicrobial technology combines a nontoxic compound, called photosensitizer, visible light of the appropriate wavelength, and the generation of reactive oxygen species. In this work, the photosensitizers TMPyP and ZnTPPS4 are investigated for photodynamic and antimicrobial photodynamic therapy. We tested these two porphyrins on two cell lines and two bacterial strains to compare effectiveness. In addition, we applied photosensitizers bound in the complex created with hp-beta-cyclodextrin. The light-emitting diodes were used at the d

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Microbiological Research

ISSN

0944-5013

e-ISSN

—

Volume of the periodical

169

Issue of the periodical within the volume

2-3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

163-170

UT code for WoS article

000330335600007

EID of the result in the Scopus database

—