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Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10210465" target="_blank" >RIV/00216208:11310/14:10210465 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388955:_____/14:00426367

  • Result on the web

    <a href="http://dx.doi.org/10.1002/elan.201300456" target="_blank" >http://dx.doi.org/10.1002/elan.201300456</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/elan.201300456" target="_blank" >10.1002/elan.201300456</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU)

  • Original language description

    An application of the flow differential pulse voltammetry with tubular detector based on silver solid amalgam for determination of antineoplastic drug lomustine in pharmaceutical preparations is presented. The highest sensitivity was obtained in [0.10moldm(-3) MES; 2.00moldm(-3) NaCl; pH6.0]:EtOH (9:1) with flow rate 0.50mLmin(-1), and the magnitude of the modulation amplitude -0.070V. The calibration dependence was linear in the range 1x10(-6)-1x10(-4)moldm(-3) (R-2=0.999). The limit of detection was 1.5x10(-7)moldm(-3). This method was successfully used for determination of lomustine in real samples of chemotherapy drug CeeNU Lomustine 40mg.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Electroanalysis

  • ISSN

    1040-0397

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    6

  • Pages from-to

    306-311

  • UT code for WoS article

    000331982500011

  • EID of the result in the Scopus database