Common mechanisms of pain and depression: are antidepressants also analgesics?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10218702" target="_blank" >RIV/00216208:11310/14:10218702 - isvavai.cz</a>

Alternative codes found

RIV/67985823:_____/14:00427829 RIV/00216208:11110/14:10218702 RIV/00216208:11120/14:43908389 RIV/00064165:_____/14:10218702

Result on the web

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00099" target="_blank" >http://dx.doi.org/10.3389/fnbeh.2014.00099</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00099" target="_blank" >10.3389/fnbeh.2014.00099</a>

Result language

angličtina

Original language name

Common mechanisms of pain and depression: are antidepressants also analgesics?

Original language description

Neither pain, nor depression exist as Independent phenomena per se, they are highly subjective inner states, formed by our brain and built on the bases of our experiences, cognition and emotions. Chronic pain is associated with changes in brain physiology and anatomy. It has been suggested that the neuronal activity underlying subjective perception of chronic pain may be divergent from the activity associated with acute pain. We will discuss the possible common pathophysiological mechanism of chronic pain and depression with respect to the default mode network of the brain, neuroplasticity and the effect of antidepressants on these two pathological conditions. The default mode network of the brain has an important role in the representation of introspective mental activities and therefore can be considered as a nodal point, common for both chronic pain and depression. Neuroplasticity which involves molecular, cellular and synaptic processes modifying connectivity between neurons and ne

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Behavioral Neuroscience

ISSN

1662-5153

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

Mar 25

Country of publishing house

CH - SWITZERLAND

Number of pages

12

Pages from-to

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UT code for WoS article

000333330000001

EID of the result in the Scopus database

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