Asymmetric Domino Aza-Michael Addition/[3+2] Cycloaddition Reactions as a Versatile Approach to alpha,beta,gamma,-Triamino Acid Derivatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10277920" target="_blank" >RIV/00216208:11310/14:10277920 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/14:00427700
Result on the web
<a href="http://dx.doi.org/10.1021/ol403660w" target="_blank" >http://dx.doi.org/10.1021/ol403660w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/ol403660w" target="_blank" >10.1021/ol403660w</a>
Alternative languages
Result language
angličtina
Original language name
Asymmetric Domino Aza-Michael Addition/[3+2] Cycloaddition Reactions as a Versatile Approach to alpha,beta,gamma,-Triamino Acid Derivatives
Original language description
Nonproteinogenic amino acids are prepared by an unprecedented domino aza-Michael addition-1,3-dipolar cycloaddition, leading to enantiopure highly substituted pyrrolidinopyrazolines. Nonaflyl azide serves as highly effective diazo transfer reagent, forming the link between the conjugate addition and cycloaddition steps. The resulting pyrrolidinopyrazolines can be rapidly transformed to either alpha,beta,gamma-triamino acids or 3,4-methano-beta-prolines. Peptide coupling can be regioselectively conductedat each of the amino groups.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Organic Letters
ISSN
1523-7060
e-ISSN
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Volume of the periodical
16
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
1088-1091
UT code for WoS article
000331926800015
EID of the result in the Scopus database
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