Lactase Persistence Variants in Arabia and in the African Arabs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10282209" target="_blank" >RIV/00216208:11310/14:10282209 - isvavai.cz</a>

Alternative codes found

RIV/67985912:_____/14:00431985

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Lactase Persistence Variants in Arabia and in the African Arabs

Original language description

Lactase persistence (LP), the state enabling the digestion of milk sugar in adulthood, occurs only in some human populations. The convergent and independent origin of this physiological ability in Europe and Africa is linked with animal domestication that either had started in both places independently or had spread from the Near East by acculturation. However, it has recently been shown that at least in its southern parts, the population of Arabia not only has a diffferent LP-associated mutation profile than the rest of Africa and Europe but also had experienced an independent demographic expansion occurring before the Neolithic around the Pleistocene-Holocene boundary. In Arabia, LP is associated with mutation -13,915*G and not, as in Europe, with -13,910*T or, as in Africa, with -13,907*G and -14,010*C. We show here that, in Arabia, -13,915*G frequency conforms to a partial clinal pattern and that this specific mutation has likely been spread from Arabia to Africa only recently from

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

AC - Archaeology, anthropology, ethnology

OECD FORD branch

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Project

<a href="/en/project/GA13-37998S" target="_blank" >GA13-37998S: Genetic imprints of food-production systems in human populations</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Human Biology

ISSN

0018-7143

e-ISSN

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Volume of the periodical

86

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

12

Pages from-to

7-18

UT code for WoS article

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EID of the result in the Scopus database

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