Difference of neuro- and immunomodulatory steroids and selected hormone and lipid concentrations between Toxoplasma-free and Toxoplasma-infected but not CMV-free and CMV-infected schizophrenia patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10287304" target="_blank" >RIV/00216208:11310/14:10287304 - isvavai.cz</a>

Alternative codes found

RIV/00023761:_____/14:#0000452 RIV/00023752:_____/14:43914576

Result on the web

<a href="https://web.natur.cuni.cz/flegr/pdf/schizosteroids.pdf" target="_blank" >https://web.natur.cuni.cz/flegr/pdf/schizosteroids.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Difference of neuro- and immunomodulatory steroids and selected hormone and lipid concentrations between Toxoplasma-free and Toxoplasma-infected but not CMV-free and CMV-infected schizophrenia patients

Original language description

OBJECTIVES: Toxoplasma gondii, the protozoan parasite infecting about 30% population worldwide, is suspected to be the etiological agent of certain form of schizophrenia disease. Toxoplasma is known to change levels of certain neurotransmitters, cytokines and several hormones in both infected animals and humans. A common feature of toxoplasmosis and schizophrenia is a disorder of immune system. METHODS: Here we studied the levels of five neuro- and immunomodulatory steroids, selected hormones and lipidsin sera of 173 schizophrenia patients. RESULTS: Toxoplasma infected schizophrenia patients expressed only insignificantly lower concentration of neuro-and immunomodulatory DHEA metabolites. Infected women had higher concentration of glucose while infected men had higher concentration of cholesterol and LDL cholesterol. No significant effect of human cytomegalovirus infection on the concentration of the above parameters was observed. The difference in the concentration of DHEA metabolite

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EG - Zoology

OECD FORD branch

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Project

<a href="/en/project/GAP303%2F11%2F1398" target="_blank" >GAP303/11/1398: Startle reaction and prepulse inhibition in human with latent toxoplasmosis</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

35

Issue of the periodical within the volume

1

Country of publishing house

SE - SWEDEN

Number of pages

8

Pages from-to

20-27

UT code for WoS article

000340153500004

EID of the result in the Scopus database

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