The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10290821" target="_blank" >RIV/00216208:11310/14:10290821 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/14:00426308
Result on the web
<a href="http://dx.doi.org/10.1007/s00335-014-9506-2" target="_blank" >http://dx.doi.org/10.1007/s00335-014-9506-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00335-014-9506-2" target="_blank" >10.1007/s00335-014-9506-2</a>
Alternative languages
Result language
angličtina
Original language name
The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus
Original language description
Reproductive barriers exist between the house mouse subspecies, Mus musculus musculus and M. m. domesticus, members of the Mus musculus species complex, primarily as a result of hybrid male infertility, and a hybrid zone exists where their ranges intersect in Europe. Using single nucleotide polymorphisms (SNPs) diagnostic for the two taxa, the extent of introgression across the genome was previously compared in these hybrid populations. Sixty-nine of 1316 autosomal SNPs exhibited reduced introgression in two hybrid zone transects suggesting maladaptive interactions among certain loci. One of these markers is within a region on chromosome 11 that, in other studies, has been associated with hybrid male sterility of these subspecies. We assessed sequencevariation in a 20 Mb region on chromosome 11 flanking this marker, and observed its inclusion within a roughly 150 kb stretch of DNA showing elevated sequence differentiation between the two subspecies. Four genes are associated with this
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.20.0303" target="_blank" >EE2.3.20.0303: Next-generation technologies in evolutionary genetics</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mammalian Genome
ISSN
0938-8990
e-ISSN
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Volume of the periodical
25
Issue of the periodical within the volume
5-6
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
223-234
UT code for WoS article
000336388400005
EID of the result in the Scopus database
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