Regiocontroled Palladium-Catalysed Direct Arylation at Carbon C2 of Benzofurans using Benzenesulfonyl Chlorides as the Coupling Partners

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10293738" target="_blank" >RIV/00216208:11310/14:10293738 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/cctc.201301077" target="_blank" >http://dx.doi.org/10.1002/cctc.201301077</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cctc.201301077" target="_blank" >10.1002/cctc.201301077</a>

Result language
angličtina
Original language name
Regiocontroled Palladium-Catalysed Direct Arylation at Carbon C2 of Benzofurans using Benzenesulfonyl Chlorides as the Coupling Partners
Original language description
The regioselective palladium-catalysed direct arylation of benzofurans with aryl halides is a challenging reaction because carbons C2 and C3 display similar reactivity. Such couplings generally lead to mixtures of C2 and C3 arylation products together with C2,C3 diarylation products. We found that the use of benzenesulfonyl chlorides instead of aryl halides as the coupling partner allows for controlling the regioselectivity of the palladium-catalysed arylation of benzofurans in favour of carbon C2. Thismethod tolerates a variety of substituents on the benzenesulfonyl derivative.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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