Antibody response of definitive hosts against antigens of two life stages of the neuropathogenic schistosome Trichobilharzia regenti
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10312030" target="_blank" >RIV/00216208:11310/15:10312030 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1186/s13071-015-1007-y" target="_blank" >http://dx.doi.org/10.1186/s13071-015-1007-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13071-015-1007-y" target="_blank" >10.1186/s13071-015-1007-y</a>
Alternative languages
Result language
angličtina
Original language name
Antibody response of definitive hosts against antigens of two life stages of the neuropathogenic schistosome Trichobilharzia regenti
Original language description
Background: The nasal avian schistosome Trichobilharzia regenti spends part of its intravertebrate period of life within the central nervous system. Migration of the parasites can be accompanied by neuromotor disorders or paralysis in natural definitivehosts (ducks) and even in laboratory mammals. Cercariae are also able to penetrate human skin and induce cercarial dermatitis. While the cellular and antibody responses against cercariae and migrating schistosomula have been investigated in mice, littleis known about immune reactions in birds. This study first describes the dynamics of antibody response in infected ducks and identifies frequently recognized antigens that may serve as diagnostic markers of infection by T. regenti. Methods: Groups of 35domestic ducks and 10 mallards were exposed to different doses of T. regenti cercariae. Sera were collected at predefined time intervals and tested by ELISA for the presence of specific anti-cercarial IgY and IgM. Antigens recognized by t
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA13-29577S" target="_blank" >GA13-29577S: The neurotropic schistosome Trichobilharzia regenti in vertebrates: immune response, pathology and diagnostic markers</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Parasites and Vectors
ISSN
1756-3305
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
JUL 28 2015
Country of publishing house
GB - UNITED KINGDOM
Number of pages
17
Pages from-to
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UT code for WoS article
000358488300004
EID of the result in the Scopus database
2-s2.0-84938091192