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Prediction of retention characteristics of heterocyclic compounds

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10314844" target="_blank" >RIV/00216208:11310/15:10314844 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/15:10314844

  • Result on the web

    <a href="http://link.springer.com/article/10.1007/s00216-015-9067-6/fulltext.html" target="_blank" >http://link.springer.com/article/10.1007/s00216-015-9067-6/fulltext.html</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00216-015-9067-6" target="_blank" >10.1007/s00216-015-9067-6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Prediction of retention characteristics of heterocyclic compounds

  • Original language description

    The CORAL software was used to build up quantitative structure-property relationships (QSPRs) for the retention characteristics of 93 derivatives of three groups of heterocyclic compounds: 2-phenyl-1,3-benzoxazoles, 4-benzylsulfanylpyridines, and benzoxazines. The QSPRs are one-variable models based on the optimal descriptors calculated from the molecular structure represented by simplified molecular input-line entry systems (SMILES). Each symbol (or two undivided symbols) of SMILES is characterized bycorrelation weight. The optimal descriptor is the sum of the correlation weights. The numerical data on the correlation weights were calculated with the Monte Carlo method by the manner which provides best correlation between endpoint and optimal descriptor for the calibration set. The predictive ability of the model is checked with the validation set (compounds invisible during building up of the model). The approach has been checked with three random splits into the training, calibrati

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical and Bioanalytical Chemistry

  • ISSN

    1618-2642

  • e-ISSN

  • Volume of the periodical

    407

  • Issue of the periodical within the volume

    30

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

    9185-9189

  • UT code for WoS article

    000365865200022

  • EID of the result in the Scopus database

    2-s2.0-84948095289