Natural hybrid of Leishmania infantum/L. donovani: development in Phlebotomus tobbi, P-perniciosus and Lutzomyia longipalpis and comparison with non-hybrid strains differing in tissue tropism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10315071" target="_blank" >RIV/00216208:11310/15:10315071 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s13071-015-1217-3" target="_blank" >http://dx.doi.org/10.1186/s13071-015-1217-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13071-015-1217-3" target="_blank" >10.1186/s13071-015-1217-3</a>

Result language

angličtina

Original language name

Natural hybrid of Leishmania infantum/L. donovani: development in Phlebotomus tobbi, P-perniciosus and Lutzomyia longipalpis and comparison with non-hybrid strains differing in tissue tropism

Original language description

Infection caused by parasites from L. donovani complex can manifest as a serious visceral disease or a self-healing milder cutaneous form. In Cukurova region in Turkey we previously identified a major focus of cutaneous leishmaniasis caused by L. donovani/infantum hybrids (CUK strain) and isolated this parasite from the locally abundant sand fly, Phlebotomus tobbi. Here, we present the first experimental study with P. tobbi. We tested the susceptibility of this species to various Leishmania under laboratory conditions, characterized glycoproteins in the P. tobbi midgut putatively involved in parasite-vector interaction and compared the development of the CUK strain in the sand fly with one other dermotropic and three viscerotropic strains belonging tothe L. donovani complex. High infection rates, heavy parasite loads and late-stage infection with colonization of the stomodeal valve were observed in P. tobbi infected by Leishmania major or L. infantum CUK hybrid. In parallel, lectin bl

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EG - Zoology

OECD FORD branch

—

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Parasites and Vectors

ISSN

1756-3305

e-ISSN

—

Volume of the periodical

8

Issue of the periodical within the volume

November

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

—

UT code for WoS article

000365331100002

EID of the result in the Scopus database

2-s2.0-84947914015