A common variant near BDNF is associated with dietary calcium intake in adolescents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10316446" target="_blank" >RIV/00216208:11310/15:10316446 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/15:43909892 RIV/00023761:_____/15:#0000520
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0271531715001384" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0271531715001384</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.nutres.2015.06.004" target="_blank" >10.1016/j.nutres.2015.06.004</a>
Alternative languages
Result language
angličtina
Original language name
A common variant near BDNF is associated with dietary calcium intake in adolescents
Original language description
Specific targets for most obesity candidate genes discovered by genomewide association studies remain unknown. Such genes are often highly expressed in the hypothalamus, indicating their role in energy homeostasis. We aimed to evaluate the associations of selected gene variants with adiposity and dietary traits. Anthropometric parameters, fat mass, dietary intake (total energy, fat, protein, carbohydrate, fiber, and calcium) and 10 gene variants (in/near TMEM18, SH2B1, KCTD15, PCSK1, BDNF, SEC16B, MC4Rand FTO) were analyzed in 1953 Czech individuals aged 10.0 to 18.0 years (1035 nonoverweight and 918 overweight: body mass index [BMI] }= 90th percentile). Obesity risk alleles of TMEM18 rs7561317, SEC16B rs10913469, and FTO rs9939609 were related to increased body weight and BMI (P < .005). The FTO variant also showed a significant positive association with waist circumference and fat mass (P < .001). Overweight adolescents had a lower total energy intake (P < .001) but a higher percent
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrition Research
ISSN
0271-5317
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
766-773
UT code for WoS article
000361416900003
EID of the result in the Scopus database
2-s2.0-84940901115