Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10317385" target="_blank" >RIV/00216208:11310/15:10317385 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/ijos.2014.75" target="_blank" >http://dx.doi.org/10.1038/ijos.2014.75</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/ijos.2014.75" target="_blank" >10.1038/ijos.2014.75</a>
Alternative languages
Result language
angličtina
Original language name
Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster)
Original language description
Continuously growing incisors are common to all rodents, which include the Microtus genus of voles. However, unlike many rodents, voles also possess continuously growing molars. Here, we report spontaneous molar defects in a population of Prairie voles (Microtus ochrogaster). We identified bilateral protuberances on the ventral surface of the mandible in several voles in our colony. In some cases, the protuberances broke through the cortical bone. The mandibular molars became exposed and infected, and the maxillary molars entered the cranial vault. Visualisation upon soft tissue removal and microcomputed tomography (microCT) analyses confirmed that the protuberances were caused by the overgrowth of the apical ends of the molar teeth. We speculate thatthe unrestricted growth of the molars was due to the misregulation of the molar dental stem cell niche. Further study of this molar phenotype may yield additional insight into stem cell regulation and the evolution and development of cont
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of oral science
ISSN
1674-2818
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
1
Country of publishing house
CN - CHINA
Number of pages
4
Pages from-to
23-26
UT code for WoS article
000351189700005
EID of the result in the Scopus database
2-s2.0-84925440852