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Targeted nanoparticles - a promising opportunity in cancer therapy - Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F16%3A10323500" target="_blank" >RIV/00216208:11310/16:10323500 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/16:10323500 RIV/00064203:_____/16:10323500

  • Result on the web

    <a href="http://web2.mendelu.cz/af_239_nanotech/J_Met_Nano/0415/pdf/JMN4-2016-01.pdf" target="_blank" >http://web2.mendelu.cz/af_239_nanotech/J_Met_Nano/0415/pdf/JMN4-2016-01.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Targeted nanoparticles - a promising opportunity in cancer therapy - Review

  • Original language description

    Nanoparticles as drug delivery vehicles pose an exciting and promising future for cancer treatment, and offer particular benefits not only for cancer treatment, but also for overcoming of multidrug resistance in cancer tissues. Targeted delivery of anti-neoplastic drugs by nanoparticles promises enhanced drug efficacy, selectivity and reduced systemic toxicity. Nanoparticle systems have unique properties that allow for both passive and active targeting of tumors. Active targeting of nanoparticles, that usually involve surface proteins known to be upregulated in cancer cells, increases accumulation in a tumor. Targeting molecules include antibodies or their fragments, aptamers, or small molecules. This review describes a comprehensive overview of different targeting of nanodrugs.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA14-18344S" target="_blank" >GA14-18344S: Development of nanoparticle-based cytostatics and enzymes for enhanced chemotherapy of human neuroblastomas and study of mechanisms of their action</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Metallomics and Nanotechnologies [online]

  • ISSN

    2336-3940

  • e-ISSN

  • Volume of the periodical

    2

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    6-11

  • UT code for WoS article

  • EID of the result in the Scopus database