Hyaluronidase Activity in Saliva of European Culicoides (Diptera: Ceratopogonidae)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F16%3A10324110" target="_blank" >RIV/00216208:11310/16:10324110 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/jme/tjv147" target="_blank" >http://dx.doi.org/10.1093/jme/tjv147</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/jme/tjv147" target="_blank" >10.1093/jme/tjv147</a>

Result language
angličtina
Original language name
Hyaluronidase Activity in Saliva of European Culicoides (Diptera: Ceratopogonidae)
Original language description
Biting midges of the genus Culicoides transmit pathogens of veterinary importance such as bluetongue virus (Reoviridae: Orbivirus). The saliva of Culicoides is known to contain bioactive molecules including peptides and proteins with vasodilatory and immunomodulative properties. In this study, we detected activity of enzyme hyaluronidase in six Culicoides species that commonly occur in Europe and that are putative vectors of arboviruses. Hyaluronidase was present in all species studied, although its molecular size, sensitivity to SDS, and substrate specificity differed between species. Further studies on the potential effect of hyaluronidase activity on the vector competence of Culicoides species for arboviruses would be beneficial.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Project
<a href="/en/project/LD14076" target="_blank" >LD14076: Pathogen detection and development in blood-sucking vectors</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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