Voltammetry at a Hanging Mercury Drop Electrode as a Tool for the Study of the Interaction of Double-stranded DNA with Genotoxic 4-Nitrobiphenyl
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F16%3A10326155" target="_blank" >RIV/00216208:11310/16:10326155 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/elan.201600241" target="_blank" >http://dx.doi.org/10.1002/elan.201600241</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elan.201600241" target="_blank" >10.1002/elan.201600241</a>
Alternative languages
Result language
angličtina
Original language name
Voltammetry at a Hanging Mercury Drop Electrode as a Tool for the Study of the Interaction of Double-stranded DNA with Genotoxic 4-Nitrobiphenyl
Original language description
Differential pulse voltammetry, cyclic voltammetry, alternating current voltammetry, and chronocoulometry at a hanging mercury drop electrode (HMDE) and DNA modified HMDE were used for the study of the interaction of 4-nitrobiphenyl (4-NBP) with double-stranded DNA and for the detection of DNA damage caused by its interaction with 4-NBP. Moreover, the interaction of DNA with intermediates of the 4-NBP reduction and with 4-aminobiphenyl, a metabolite of 4-NBP, was investigated. The mechanism of the electrochemical reduction of 4-NBP was investigated using CV, too. It was found that the reduction of 4-NBP is controlled by both diffusion and adsorption. The rate constant of the reduction and the diffusion coefficient were calculated as well.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electroanalysis
ISSN
1040-0397
e-ISSN
—
Volume of the periodical
28
Issue of the periodical within the volume
11
Country of publishing house
DE - GERMANY
Number of pages
11
Pages from-to
2760-2770
UT code for WoS article
000387891400017
EID of the result in the Scopus database
2-s2.0-84978221580